SMART UI

Precision Risk Analysis of Cancer Therapy with Interactive Nomograms and Survival Plots

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Authors

G. Elisabeta MaraiChihua MaAndrew BurksFilippo PellolioGuadalupe CanahuateDavid M. VockAbdallah S.R. MohamedC. David Fuller

Abstract

We present the design and evaluation of an integrated problem solving environment for cancer therapy analysis. The environment intertwines a statistical martingale model and a K Nearest Neighbor approach with visual encodings, including novel interactive nomograms, in order to compute and explain a patient's probability of survival as a function of similar patient results. A coordinated views paradigm enables exploration of the multivariate, heterogeneous and few-valued data from a large head and neck cancer repository. A visual scaffolding approach further enables users to build from familiar representations to unfamiliar ones.